HORDB

ID: hor006545
Uniprot ID: P51921
Protein name: GnRH-associated peptide 3
Gene name: gnrh3
Organism: Pagrus major (Red sea bream) (Chrysophrys major)
Family: GnRH family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Pagrus (genus), Sparidae (family), Spariformes (order), Eupercaria, Percomorphaceae, Euacanthomorphacea, Acanthomorphata, Ctenosquamata, Eurypterygia, Neoteleostei, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: SVGELEATIRMMGTGGVVSLPEEASAQTQERLRPYNVIKDDSSHFD
Length: 46(37-82)
Propeptide: MEASSRVTVQVLLLALVVQVTLSQHWSYGWLPGGKRSVGELEATIRMMGTGGVVSLPEEASAQTQERLRPYNVIKDDSSHFDRKKRFPNK
Signal peptide: MEASSRVTVQVLLLALVVQVTLS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor006545_AF2.pdb

hor006545_ESM.pdb

Mass:	582538	Formula:	C213H343N61O75S2
Absent amino acids:	CW	Common amino acids:	ES
pI:	4.29	Basic residues:	5
Polar residues:	14	Hydrophobic residues:	13
Hydrophobicity:	-48.04	Boman Index:	-10012
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	74.13
Instability Index:	3759.35	Extinction Coefficient cystines:	1490
Absorbance 280nm:	33.11

PubMed ID: 7851723
Title: Molecular cloning of a cDNA encoding the prepro-salmon gonadotropin-releasing hormone of the red seabream.